Organic and Biomolecular Chemistry p. 1219 - 1224 (2011)
Update date:2022-08-03
Topics:
Kobayashi, Takaaki
Arisawa, Mitsuhiro
Shuto, Satoshi
A synthetic method for bicyclic heterocycles, such as indole, benzofuran and chromene derivatives bearing a chiral cyclopropane at the 2-position, was established using isomerization of a terminal olefin and enamide-ene or diene metathesis. This route can also be applied to chiral 2-cyclopropylquinoline synthesis (both cis and trans).
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