Chemistry and anti-HIV activity of 2'-β-fluoro-2',3'-dideoxyguanosine

Article abstract of DOI:10.1080/15257779408013236

The 2'-β-fluoro analogue of 2',3'-dideoxyguanosine has been prepared by two synthetic routes. This compound and two analogues have anti-HIV activity in at least two of three host cell systems used (ATH8, CEM, PBL). These compounds, as well as their ddGuo

Full text of DOI:10.1080/15257779408013236

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Chemistry and Anti-HIV Activity of 2′-β-
Fluoro-2′,3′-dideoxyguanosine
Harry Ford Jr. a , John S. Driscoll a , Maqbool Siddiqui a , James A.
Kelley a , Hioraki Mitsuya b , Takuma Shirasaka b , David G. Johns a
Victor E. Marquez a
&
a Laboratory of Medicinal Chemistry, Developmental Therapeutics
Program , 9000 Rockville Pike, Building 37, Room 5C-02, Bethesda,
MD, 20892
b Experimental Retrovirology Section, Medicine Branch, Clinical
Oncology Program, Division of Cancer Treatment, National Cancer
Institute, National Institutes of Health , 9000 Rockville Pike, Building
37, Room 5C-02, Bethesda, MD, 20892
Published online: 23 Sep 2006.
To cite this article: Harry Ford Jr. , John S. Driscoll , Maqbool Siddiqui , James A. Kelley , Hioraki
Mitsuya , Takuma Shirasaka , David G. Johns & Victor E. Marquez (1994) Chemistry and Anti-HIV
Activity of 2′-β-Fluoro-2′,3′-dideoxyguanosine, Nucleosides and Nucleotides, 13:1-3, 213-234, DOI:
10.1080/15257779408013236
To link to this article: http://dx.doi.org/10.1080/15257779408013236
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