Journal of Organic Chemistry p. 4735 - 4740 (1990)
Update date:2022-08-04
Topics: Synthesis Pyrroles Application Experimental 2-Substituted
Gupton, John T.
Krolikowski, Dale A.
Yu, Richard H.
Riesinger, Steve W.
Sikorski, James A.
A variety of 2-substituted vinamidinium salts react with α-amino acid esters under basic conditions to produce 2-carbethoxy-4-substituted-pyrroles in good yield.The overall process represents a short and efficient synthesis of highly functionalized pyrrol
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