Synthesis and cytotoxic activity of novel derivatives of 4′-demethylepipodophyllotoxin

DOI: 10.1016/j.bmcl.2004.07.094

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 5063 - 5066 (2004)

Update date:2022-08-06

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Authors:

Chen, Shi-Wu

Tian, Xuan

Tu, Yong-Qiang

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Article abstract of DOI:10.1016/j.bmcl.2004.07.094

The IC₅₀ values of 9g (n = 5, R = CH₂Ph), which is the most potent inhibitor against HL-60 and A-549 cells, are 0.04 and <0.01 μM, respectively.

Full text of DOI:10.1016/j.bmcl.2004.07.094

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