ENZYMATIC KINETIC RESOLUTION OF CYANOHYDRIN ACETATES AND ITS APPLICATION TO THE SYNTHESIS OF (S)-(-)-FRONTALIN

DOI: 10.1016/S0040-4020(01)89493-X

Source and publish data:

Tetrahedron p. 5469 - 5476 (1989)

Update date:2022-07-29

Topics:

Authors:

Ohta, Hiromichi

Kimura, Yoichi

Sugano, Yasushi

Sugai, Takeshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)89493-X

Kinetic resolution of racemic 1-cyano-1-methylalkyl and alkenyl acetates has been achieved on incubation with Pichia miso IAM 4682, which hydrolyzed selectively the (R)-enantiomer, leving behind the (S)-enantiomer intact.The chiral 1-cyano-1-methyl-5-hexenyl acetate thus obtained was converted to (S)-frontalin via unsaturated diol.

Full text of DOI:10.1016/S0040-4020(01)89493-X

Products guided by the article

Product name:(S)-methyl 2-methyl-2-hydroxy-6-heptenoate

Cas No:127725-21-7

R&D Labs maybe for 127725-21-7

SuZhou Bichal Biological Technology CO.,LTD

Contact:+86-512-68051130

Address:NO.32 huoju road HI-TECH Industrial development zone SuZhou China
Acros Pharmatech Limited

website:http://www.acrospharmatech.com

Contact:+1-3234804688

Address:Flat/RM 1502,Easey Commercial building 253-261 Hennessy Road,Wanchai，HongKong
Shanghai He Yang International Trading Co., Ltd.

Contact:+86-21-52043598

Address:Room 816, Blag.5, No.58 Huachi Road
ShangHai Original Economy-Trade Develop Co.,Ltd.,

Contact:86-21-68552131

Address:shanghai
Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd

Contact:+86-0517-87036900

Address:Chuzhou Chemical park, Huai'an, Jiangsu Province

Relevant to this article

Sequential isomerization and ring-closing metathesis: Masked styryl and vinyloxyaryl groups for the synthesis of benzo-fused heterocycles

Doi:10.1016/S0040-4039(03)01545-4
(2003)
Study of the reaction between carbamoyl azides of α-N-protected amino acids and hydrazine monohydrate

Doi:10.1002/ejoc.201001385
(2011)
Regioselective Reductive Ring Cleavage of 3-Benzyltetrahydro-1,3-oxazines to 3-Dialkylaminopropanols and of 3-Benzyl-3-methyltetrahydro-1,3-oxazinium Iodides to Alkyl 3-Dialkylaminopropyl Ethers

Doi:10.1055/s-1990-26819
(1990)
Activation of carbodiimide and transformation with amine to guanidinate group by Ln(OAr)₃(THF)₂ (Ln: Lanthanide and yttrium) and Ln(OAr)₃(THF)₂ as a novel precatalyst for addition of amines to carbodiimides: Inf

Doi:10.1021/ic200091s
(2011)
Quinolizines and indolizines. Part 16 [I]. Synthesis of pyrrolo[3,2,1-ij]quinolin-4-ones with potential fungicidal activity

Doi:10.1002/jhet.5570260609
(1989)
Synthesis of acyclic and dehydroaspartic acid analogues of Ac-Asp-Glu-OH and their inhibition of rat brain N-acetylated α-linked acidic dipeptidase (NAALA dipeptidase)

Doi:10.1021/jm00172a009
(1990)

Article Doi