Journal of Organic Chemistry p. 4925 - 4928 (1990)
Update date:2022-09-26
Topics:
Moreno-Manas, Marcial
Pleixats, Roser
Villarroya, Merce
L-Ascorbic acid (1) is efficiently allylated at C-2 with primary and secondary allylic substrates by using palladium(0) catalysis.Hydrogenation of the resulting allylated compounds 6 affords L-ascorbic acid derivatives with saturated chains at C-2.
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Doi:10.1021/jo00300a037
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