Novel Synthesis of syn-α,β-Epoxy Alcohols by Diastereoselective Carbonyl Reduction of α,β-Epoxy Ketones

Article abstract of DOI:10.1016/S0040-4039(00)78454-1

A novel tin hydride reagent, Bu3SnH-Bu4NCN, reduced α,β-epoxy ketones to the corresponding syn-α,β-epoxy alcohols in high diastereoselectivities.