Synthesis and antitubercular activity of monocyclic nitroimidazoles: Insights from econazole

DOI: 10.1016/j.bmcl.2010.12.128

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1515 - 1518 (2011)

Update date:2022-08-06

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Authors:

Lee, Sang-Ho

Kim, Suhyun

Yun, Min-Han

Lee, Yong Sup

Cho, Sang-Nae

Oh, Taegwon

Kim, Pilho

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Article abstract of DOI:10.1016/j.bmcl.2010.12.128

We have designed and synthesized econazole-derived nitroimidazoles to investigate the antitubercular activity of the nitroimidazole compounds. The introduction of a nitro group at the 4-position of the imidazole on econazole abolished the antitubercular a

Full text of DOI:10.1016/j.bmcl.2010.12.128

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