Expeditious synthesis of Mosher amides using a solid supported carbodiimide

DOI: 10.1016/0040-4039(96)01617-6

Source and publish data:

Tetrahedron Letters p. 7171 - 7172 (1996)

Update date:2022-08-05

Topics:

Authors:

Adamczyk, Maciej

Fishpaugh, Jeffrey R.

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Article abstract of DOI:10.1016/0040-4039(96)01617-6

A novel method of Mosher amide synthesis using a solid supported carbodiimide in CDCl₃ is described. Estimation of optical purity can be promptly achieved by direct NMR analysis of the reaction solvent.

Full text of DOI:10.1016/0040-4039(96)01617-6

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