PREPARATION, REACTIVITY, AND NEUROTOXICITY OF TRYPTAMINE-4,5-DIONE

DOI: 10.1016/S0040-4039(00)94405-8

Source and publish data:

Tetrahedron Letters p. 969 - 972 (1990)

Update date:2022-08-05

Topics:

Authors:

Cai, Ping

Snyder, John K.

Chen, Jin-Chung

Fine, Richard

Volicer, Ladislav

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)94405-8

Tryptamine-4,5-dione protected as the carbamate was pepared in excellent overall yield by the oxidation of serotonin carbamate with benzeneseleninic anhydride.This o-quinone, which was potently neurotoxic, readily added sulfur nucleophiles under basic conditions including cysteine and glutathione in 1,4-fashion, a reactivity pattern which may reflect the mechanism of the neurotoxicity.

Full text of DOI:10.1016/S0040-4039(00)94405-8

Products guided by the article

Product name:[2-(4,5-Dioxo-7-phenylsulfanyl-4,5-dihydro-1H-indol-3-yl)-ethyl]-carbamic acid ethyl ester

Cas No:128766-46-1

R&D Labs maybe for 128766-46-1

SHANGHAI ARCADIA BIOTECHNOLOGY LTD.

Contact:+86-21-61353236

Address:SUITE 901, BUILDING WENSLI, 1378 LU JIA BANG RD, SHANGAHI 200011, P.R.CHINA
Second Pharma Co., Ltd

Contact:+86-575-82733999 0575-82732999

Address:hangzhou gulf fine chemical zone,shangyu city,zhejiang province
HANWAYS CHEMPHARM CO.,LIMITED

website:http://www.hanwayschem.com

Contact:+86-18502787239(whatsapp)-

Address:18-1-802, Green Garden, Jianghan District, Wuhan 430023, China
Shaanxi Lighte Optoelectronics Material Co., Ltd.

Contact:+86-29-88320728-622/619/620

Address:No.55 INDUSTRY ROAD 2,XI'AN NATIONAL CIVIL AEROSPACE INDUSTRIAL PARK.XI'AN China 710065.
Sichuan Mianzhu Ronghong Chemical Co.,LTd

Contact:8613981840544

Address:XINSHI INDUSTRY PARK,MIANZHU,SICHUAN,CHINA

Relevant to this article

Aminopurine and aminoquinazoline scaffolds for development of potential dengue virus inhibitors

Doi:10.1016/j.ejmech.2016.10.008
(2017)
Synthesis of fused acetal derivatives by manganic acetate promoted additions to endocyclic enol ethers

Doi:10.1016/S0040-4020(01)87230-6
(1993)
Alcohol mediated synthesis of 4-oxo-2-aryl-4H-chromene-3-carboxylate derivatives from 4-hydroxycoumarins

Doi:10.1021/jo301044y
(2012)
Facile preparation of 2-substituted benzoxazoles and benzothiazoles via aerobic oxidation of phenolic and thiophenolic imines catalyzed by polymer-incarcerated platinum nanoclusters

Doi:10.1002/adsc.201100430
(2011)
CC-1065 partial structures: Enhancement of noncovalent affinity for DNA minor groove binding through introduction of stabilizing electrostatic interactions

Doi:10.1021/jo00030a042
(1992)
SYNTHESIS OF CLEONINE, AMINO(1-HYDROXYCYCLOPROPYL)ACETIC ACID, A NOVEL AMINO ACID CONTAINED IN CLEOMYCIN

Doi:10.1016/S0040-4039(00)71156-7
(1980)

Article Doi