Synthesis and Characterization of Nucleoside Peptides: Toward Chemical Ribonucleases. 1

DOI: 10.1021/jo00304a026

Source and publish data:

Journal of Organic Chemistry p. 5125 - 5132 (1990)

Update date:2022-08-04

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Authors:

Bashkin, James K.

Gard, Janice K.

Modak, Anil S.

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Article abstract of DOI:10.1021/jo00304a026

Site-selective cleavage of nucleic acids by chemical analogues of nuclease enzymes is an area of major interest.Since imidazole is known to catalyze the hydrolysis of RNA, we postulated that oligonucleotides with pendant imidazole groups could be used to

Full text of DOI:10.1021/jo00304a026

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