Chirospecific synthesis of amino acids, amino aldehydes and amino alcohols from D-glucosamine hydrochloride. A multigram synthesis of N-BOC-L-serinal

DOI: 10.1016/S0040-4039(00)88778-X

Source and publish data:

Tetrahedron Letters p. 1253 - 1256 (1990)

Update date:2022-08-04

Topics:

Authors:

Giannis Giannis

Henk Henk

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Article abstract of DOI:10.1016/S0040-4039(00)88778-X

N-tert.-butyloxycarbonyl-L-serinal 4 was readily prepared from D-glucosamine hydrochloride 1 in three steps. The versatile synthetic intermediate 4 is chemically and configurationally stable for prolonged time and reacts with various stabilized phosphorus

Full text of DOI:10.1016/S0040-4039(00)88778-X

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Product name:((E)-(R)-1-Hydroxymethyl-4-oxo-4-phenyl-but-2-enyl)-carbamic acid tert-butyl ester

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