Solid-phase synthesis of 3,5-disubstituted 1,3-oxazolidin-2-ones by an activation/cyclo-elimination process

Article abstract of DOI:10.1016/S0040-4039(98)01608-6

Polymer-supported sulfonyl chloride is used in the solid-phase synthesis of disubstituted 1,3-oxazolidin-2-ones. The target compounds were prepared by attaching 1,2-diols to the solid support, followed by reaction with p- toluenesulfonyl isocyanate and su