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g) or 2 h (3a–g). The water was extracted with diethyl ether (3ϫ).
The combined organic layers were dried with Na2SO4 and filtered,
and the solvent was removed under vacuum. All the reaction prod-
ucts were purified by flash chromatography. The yields reported in
Tables 1–3 refer to isolated products and the Z/E ratios were mea-
sured on the crude by NMR spectroscopy. All isolated compounds
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1
were fully characterized by GC–MS and H NMR and 13C NMR
spectroscopy.
Supporting Information (see footnote on the first page of this arti-
cle): Experimental details and characterization data for the new
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Acknowledgments
Financial support from Ministero Italiano Università e Ricerca
(MIUR, National Projects PRIN2007, Progetto di Ricerca
dЈInteresse Nazionale), Consorzio Interuniversitario Nazionale di
Metodologie e Processi Innovativi di Sintesi (CINMPIS), Bari, and
the University of Perugia is gratefully acknowledged. Technical
contributions of Dr. Gianni Pintus for collecting some of the results
reported in Table 2 are particularly appreciated.
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Received: January 12, 2011
Published Online: February 23, 2011
Eur. J. Org. Chem. 2011, 1848–1851
© 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
www.eurjoc.org
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