Asymmetric Synthesis of (R)- and (S)-4-(Substituted Benzyl)dihydrofuran-2(3H)-ones: An Application of the Ruthenium-binap Complex-catalysed Asymmetric Hydrogenation of Alkylidenesuccinic Acids

DOI: 10.1039/P19900001441

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 1441 - 1445 (1990)

Update date:2022-08-05

Topics:

Authors:

Shao, Liming

Miyata, Shiro

Muramatsu, Hitoshi

Kawano, Hiroyuki

Ishii, Youichi

et al. et al.

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Article abstract of DOI:10.1039/P19900001441

A concise synthesis of (S)- or (R)-4-(substituted benzyl)dihydrofuran-2(3H)-ones (1) with high enantiomeric purity is presented. (S)- or (R)-(Substituted benzyl)succinic acids (6) <*> 97percent enantiomeric excess) were first prepared by Ru2Cl4<(R)- or (S

Full text of DOI:10.1039/P19900001441

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