ENANTIOSELECTIVE SYNTHESIS OF HYDROXY α-AMINO ACIDS. (-)-erythro- and (-)-threo-γ-HYDROXYNORVALINES

Article abstract of DOI:10.1016/S0040-4020(01)89761-1

The amino acids (-)-erythro- and (-)-threo-γ-hydroxynorvaline have been synthesized from D-ribonolactone, 6, as single chiral precursor.Moreover, β-hydroxy-α-azido-γ-valerolactones 12a and 12b have been also prepared from 6 in two different alternative wa