Journal of Heterocyclic Chemistry p. 1025 - 1030 (1990)
Update date:2022-08-05
Topics:
Anderson
Mach
A series of C-5 substituted pyrrolizine biscarbamate alkylating agents were synthesized and evaluated in an in vitro alkylation assay. Introduction of electron-withdrawing substituents at the C-5 position resulted in a dramatic decrease in chemical reactivity toward the model nucleophile 4-(4-nitrobenzyl)pyridine (NBP).
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Doi:10.1016/j.bmcl.2013.02.028
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(2015)Doi:10.1016/S0040-4020(01)86683-7
(1990)Doi:10.1002/jhet.5570270357
(1990)Doi:10.1016/j.tetlet.2014.12.112
(2015)Doi:10.1021/jo1023574
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