European Journal of Medicinal Chemistry p. 321 - 325 (1990)
Update date:2022-08-05
Topics:
Vanelle
Maldonado
Jentzer
Crozet
Savornin
Delmas
Gasquet
Timon-David
New imidazole compounds with pharmacological activity were obtained after subjecting 1-methyl-2-formyl-5-nitroimidazole to classical organic reactions: aldimine production, Knoevenagel reaction, and 4-ylidenebutenolide production. Some of these compounds exhibit significant antiparasitic activities against amoebae, trichomonas and leishmania.
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Doi:10.1039/DT9900001747
(1990)Doi:10.1016/0022-328X(93)80236-5
(1993)Doi:10.1021/jo200337v
(2011)Doi:10.1039/d0ob01812k
(2020)Doi:10.1016/0040-4039(90)80131-5
(1990)Doi:10.1002/anie.201907943
(2019)