FORMATION AND REACTIVITY OF HIGHLY STABILIZED CARBANIONS AND ENOLATES BY Pd-CATALYZED ALKYLATION OF HETEROCYCLIC COMPOUNDS

Article abstract of DOI:10.3987/COM-89-5117

Highly stabilized carbanion and enolate salts, heterocycle-substituted sodiomalononitrile and sodiocyanoacetates, were synthesized via Pd-catalyzed ring-alkylation of bromoheterocyclic compounds and shown to be useful intermediates for the synthesis of va