
Tetrahedron p. 2273 - 2280 (1990)
Update date:2022-08-04
Topics:
Donaldson, William A.
Stepuszek, Daniel J.
Gruetzmacher, James A.
A palladium mediated ring homologation-functionalization approach to the Ar-7-7 tricyclic skeleton of colchicine from 1-arylcyclohexenes is described. This methodology involves the chloropalladation of 1-aryl-7-methylenebicyclo[4.1.0]heptanes to afford ar
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