Derivatives of a Novel Cyclopeptolide. 1. Synthesis, Antifungal Activity, and Structure-Activity Relationships

DOI: 10.1021/jm00039a002

Source and publish data:

Journal of Medicinal Chemistry p. 1908 - 1917 (1994)

Update date:2022-07-29

Topics:

Authors:

Emmer, Gerhard

Grassberger, Maximilian A.

Meingassner, Josef G.

Schulz, Gerhard

Schaude, Michael

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Article abstract of DOI:10.1021/jm00039a002

The synthesis of a series of derivatives of the novel antifungal cyclopeptolide 1, which consists of nine S-amino acids and R-lactic acid, is described.Besides functional group variation of MeAsp⁴ (esters 2a-d, amides 3a-d, alcohol 4, and its d

Full text of DOI:10.1021/jm00039a002

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