Palladium Catalysis in Cephalosporin Chemistry: General Methodology for the Synthesis of Cephem Side Chains

DOI: 10.1021/jo00310a014

Source and publish data:

Journal of Organic Chemistry p. 5833 - 5847 (1990)

Update date:2022-09-26

Topics:

Authors:

Farina, Vittorio

Baker, Stephen R.

Benigni, Daniel A.

Hauck, Sheila I.

Sapino, Chester

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00310a014

We describe in full the palladium-catalyzed coupling of 3-(triflyloxy)cephems with organotin compounds, leading to the synthesis of 3-alkenyl-, 3-alkynyl-, and 3-arylcephems under exceptionally mild conditions.While this approach was not satisfactory for

Full text of DOI:10.1021/jo00310a014

Products guided by the article

Product name:(6R,7R)-7-tert-Butoxycarbonylamino-3-(1-methyl-1H-pyrrol-2-yl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

Cas No:129849-13-4

R&D Labs maybe for 129849-13-4

Hangzhou Ledun Technology Co.,Ltd.

Contact:86-571-18767088918

Address:No.6 street,XiaSha,Hangzhou,China.
Taizhou Green Peptide Trading Co., Ltd.

Contact:13736652831

Address:Room 1501, No71, Yuehe Road, Taizhou City, Zhejiang Province, China
Jiangxi Huashi Pharmaceutical Co., Ltd

Contact:+86-795-4509628

Address:Ningbo Ave., Fengtian Industrial Park, Fengxin Country, Jiangxi, China.
Lyrin Industrial Corporation Limited

Contact:86-731-82571800

Address:Rm 2408,Asia Economy International Building,Shaoshan Road South,Yuhua District,Changsha,Hunan,China
FOSHAN NANHAI ZHONGNAN PHARMACEUTICAL FACTORY

Contact:0086-0757-85609331

Address:XIAHENGTIAN INDUSTRIAL ZONE,SHAYONG VILLAGE,LISHUI TOWN

Relevant to this article

Functionalization of Alkynes and Alkenes Using a Cascade Reaction Approach: Synthesis of β-Keto Sulfones under Metal-free Conditions

Doi:10.1021/acs.joc.9b02779
(2020)
Synthesis of simple CrL₄(alkyne) complexes by displacement of a labile cyclooctadiene ligand

Doi:10.1021/ja00179a054
(1990)
1,2-Functionalization of α,β-Epoxycycloalkanones

Doi:10.1021/jo00308a007
(1990)
Ring-opening fluorination of α, β-epoxy sulfoxides: A novel synthesis of α-fluoroketones

Doi:10.1248/cpb.38.1798
(1990)
Catalytic Regiodivergent Kinetic Resolution of Allylic Epoxides: A New Entry to Allylic and Homoallylic Alcohols with High Optical Purity

Doi:10.1021/jo035674h
(2004)
THERMAL ANALYSIS OF THE OXALATE HEXAHYDRATES AND DECAHYDRATES OF YTTRIUM AND THE LANTHANIDE ELEMENTS.

Doi:10.1016/0022-5088(80)90222-2
(1980)

Article Doi