Anti-Selective Reaction of α-Sulfenyl Acetals with Silylated Carbon Nucleophiles. Scope, Limitation, and Mechanism

Article abstract of DOI:10.1021/jo00055a009

In the presence of a Lewis acid, α-sulfenyl acetals 1 reacted with various silylated carbon nucleophiles 2 to give anti adducts (anti-3) with high diastereoselectivity.The stereochemistry was only slightly affected by the reaction conditions, such as temp