Journal of Medicinal Chemistry p. 12 - 19 (1991)
Update date:2022-07-29
Topics:
Hoefle, M. L.
Blouin, L. T.
Fleming, R. W.
Hastings, S.
Hinkley, J. M.
et al.
A series of α,α-diaryl-1-piperidinebutanols was evaluated for antiarrhythmic activity in the coronary ligated dog model.Structure-activity relationship studies indicated that the 2,6-dimethylpiperidine group yielded compounds with the best antiarrhythmic
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