Journal of Medicinal Chemistry p. 1722 - 1734 (1992)
Update date:2022-09-26
Topics:
Baker, William R.
Fung, Anthony K. L.
Kleinert, Hollis D.
Stein, Herman H.
Plattner, Jacob J.
et al.
A new series of renin inhibitors has been developed.The inhibitors feature a novel replacement for the P2/P3 dipeptide moiety normally associated with renin inhibitors.The dipeptide replacement was a (2S,4S)-3-aza(or oxa)-2,4-dialkylglutaric acid amide.Ex
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