Magnetic Resonance in Chemistry p. 1130 - 1139 (1991)
Update date:2022-08-05
Topics: NMR spectroscopy Structural characterization X-ray crystallography (+/-) 3-Aryl
Arias-Perez, M. S.
Cosme, A.
Galvez, E.
Florencio, F.
Fonseca, I.
Sanz, J.
A series of (+/-)-3-aryl-1-azabicyclo<2.2.2>octan-3-ols were synthesized and studied by 1H, 13C and 2D NMR spectroscopy, and the crystal structure of (+/-)-3-(4-methylphenyl)-1-azabicyclo<2.2.2>octan-3-ol was determined by X-ray diffraction.The combined use of COSY, NOESY and 1H-13C correlation spectra of these compounds helped in the unambiguous and complete assignments of the bicyclic carbon and proton spin system.This study allows the establishment of the proton magnetic parameters for the quinuclidine moiety.Standard values of 1H-1H coupling constants are proposed in order to analyse more complex quinuclidine derivatives. KEY WORDS 3-Aryl-1-azabicyclo<2.2.2>octan-3-ols, 2D NMR (COSY, NOESY and 1H-13C correlated spectroscopy), 1H-1H coupling constants in quinuclidine derivatives
View MoreJIAXING SUNS INTERNATIONAL TRADE CO LTD
Contact:18367306858
Address:No.123,Huixin Avenue,Huimin Dist
Anhui Gusheng Import&Export CO.,LTD
Contact:86-551-63662296
Address:Jinzhai Road NO.162 ,hefei, china
Lianyungang Yunbo Chemical Co.,Ltd.
Contact:518-81066110
Address:B907,Dongsheng"Mingdu Square,21-2 East Chaoyang Road,Xinpu,(sale department)
Zhejiang Chemicals Import & Export Corporation
Contact:86-571-87043088
Address:No.37,Qingchun Road,Hangzhou,China
Lyrin Industrial Corporation Limited
Contact:86-731-82571800
Address:Rm 2408,Asia Economy International Building,Shaoshan Road South,Yuhua District,Changsha,Hunan,China
Doi:10.1016/S0040-4020(01)85587-3
(1990)Doi:10.1002/chem.201003546
(2011)Doi:10.1021/ol200940a
(2011)Doi:10.1021/jm2004128
(2011)Doi:10.2174/157017811795038368
(2011)Doi:10.1016/S0040-4020(01)87831-5
(1990)