
Tetrahedron p. 5377 - 5382 (1990)
Update date:2022-08-04
Topics:
Mann, John
Haase-Held, Margret
Springer, Caroline J.
Bagshawe, Kenneth D.
We describe the synthesis of the novel N-mustard prodrug 4-<(2-chloroethyl)(2-mesyloxyethyl)amino>benzoyl-L-glutamic acid, which is designed for activation by tumour localising antibody-carboxypeptidase conjugates.
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