Regioselective functionalization of chiral nickelacycles derived from N-protected aspartic and glutamic anhydrides

Article abstract of DOI:10.1016/S0040-4039(00)97733-5

The electrophilic cleavage of the nickelacycles resulting from oxidative addition of Ni(o) complexes to N-protected aspartic and glutamic anhydrides, followed by decarbonylation, gives rise regioselectively to derivatives of α- and β-alanine or α- and γ-aminobutyric acid, respectively.