Investigations into a Mild Diels-Alder Approach to 6-Substituted Quinazoline-2,4-dione Derivatives

Article abstract of DOI:10.1021/jo00001a046

Furo<3,4-d>pyrimidine-2,4-dione (2) has been reacted with a number of dienophiles to give the Diels-Alder adducts such as 3 and 4 under very mild reaction conditions.Methyl acrylate gives only two regioisomeric endo products which have been isolated and c