Synthesis of 17β-(3'-thiophenyl)-5β-androstane-3β,14β-diol 3-D-glucopyranoside, an anti-inotropic cardiac glucoside

Article abstract of DOI:10.1016/0039-128X(90)90026-8

In a continuing effort to synthesize cardiac glucoside analogs with modified 17β-functional groups for pharmacologic testing, we used 3β-benzyloxy-5β-androst-15-en-17-one as an efficient intermediate.This report describes a preparation of 17β-(3'-thiophen