Notable difference in anti-HIV activity of integrase inhibitors as a consequence of geometric and enantiomeric configurations

Article abstract of DOI:10.1016/j.bmcl.2013.05.050

While some examples are known of integrase inhibitors that exhibit potent anti-HIV activity, there are very few cases reported of integrase inhibitors that show significant differences in anti-HIV activity that result from distinctions in cis- and trans-c