160. Synthesis and Biological Evaluation of 14-Alkoxymorphinans - Part 7 - 14,14'-Dimethoxy Analogues of Norbinaltorphimine: Synthesis and Determination of Their χ Opioid Antagonist Selectivity

DOI: 10.1002/hlca.19900730622

Source and publish data:

Helvetica Chimica Acta p. 1779 - 1783 (1990)

Update date:2022-07-29

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Authors:

Schmidhammer, Helmut

Ganglbauer, Ernst

Mitterdorfer, Joerg

Rollinger, Judith M.

Smith, Colin F. C.

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Article abstract of DOI:10.1002/hlca.19900730622

The bimorphinans 6 and 7 have been prepared from 14-O-methylnaloxone (2) and 14-O-methylnaltrexone (3), respectively.The known compounds 2 and 3 were synthesized by a different route than the route described.Bimorphinan 7 possessed a similar ξ receptor af

Full text of DOI:10.1002/hlca.19900730622

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