Tetrahedron Letters p. 6363 - 6366 (1990)
Update date:2022-08-03
Topics:
Wada
Ishikawa
Hata
Nucleoside 3'-N,N-diisopropylphosphonamidates reacted with tris(2,4,6-tribromophenoxy)dichlorophosphorane (BDCP) to generate the corresponding aminophosphorochloridites without cleavage of the P-N bond. The reaction was applied to internucleotidic bond formation.
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