A simple and direct method for converting thioamides into thioesters

DOI: 10.1016/S0040-4020(98)01096-5

Source and publish data:

Tetrahedron p. 1187 - 1196 (1999)

Update date:2022-09-26

Topics:

Authors:

Harrowven, David C.

Lucas, Matthew C.

Howes, Peter D.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(98)01096-5

Thioamides may be transformed into thioesters through the simple expedient of warming them in an aqueous THF solution containing an alkylating agent. Reactions proceed in high yield and are amenable to multi-gram scale.

Full text of DOI:10.1016/S0040-4020(98)01096-5

Products guided by the article

Product name:methyl 2-<3-methoxyphenyl>ethanethioate

Cas No:132353-98-1

R&D Labs maybe for 132353-98-1

Changsha Botaniex Inc.

Contact:(86) 731 88718666

Address:Room 1222, Unit 4, Building B, Shangcheng, No.47, Kaiyuan East Road.
SOGA ENTERPRISES ASIA GROUP

Contact:+86-633-8332928

Address:No.1,Huanghai Yilu.Rizhao,Shandong
Nanjing Yuance Industry&Trade Co., Ltd.

website:http://www.njyuance.cn/

Contact:+86-25-85439097

Address:B1702, Aoti Bldg, No. 130, Aoti Avenue, Nanjing, China
SAGECHEM LIMITED

website:http://www.sagechem.com

Contact:+86-571-86818502

Address:Room C1301, New Youth Plaza, 8 Jia Shan Road, Hangzhou, China
ZUNYI CITY BEI YUAN CHEMICAL CO., LTD

website:http://www.china-beiyuan.com

Contact:+86-851-27751258

Address:Shawan Town, Huichuan District, Zunyi City, Guizhou Province, China

Relevant to this article

DFT and experimental study of N,N'-bis(3'-carboxy,4'-aminophenyl)-1,4- quinonediimine, a carboxyl substituted aniline trimer

Doi:10.1016/j.molstruc.2010.05.038
(2010)
Synthesis of tert-butyl peresters from aldehydes by Bu₄NI- catalyzed metal-free oxidation and its combination with the Kharasch-Sosnovsky reaction

Doi:10.1039/c1cc14602e
(2011)
Development of a Unique Heterogeneous Palladium Catalyst for the Suzuki–Miyaura Reaction using (Hetero)aryl Chlorides and Chemoselective Hydrogenation

Doi:10.1002/adsc.201700156
(2017)
Synthesis of indole and biindolyl triflones: Trifluoromethanesulfonylation of indoles with Tf₂O/TTBP (2,4,6-tri- tert -butylpyridine) system

Doi:10.1021/ol201931x
(2011)
Synthesis of Optically Active 2-Amino-1,3,4-oxadiazoles and their Hybrid Peptides

Doi:10.1002/jhet.2166
(2015)
Discovery, Synthesis, and Preclinical Characterization of N-(3-Chloro-4-fluorophenyl)-1H-pyrazolo[4,3-b]pyridin-3-amine (VU0418506), a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu₄)

Doi:10.1021/acschemneuro.6b00035
(2016)

Article Doi