A simple and direct method for converting thioamides into thioesters

DOI: 10.1016/S0040-4020(98)01096-5

Source and publish data:

Tetrahedron p. 1187 - 1196 (1999)

Update date:2022-09-26

Topics:

Authors:

Harrowven, David C.

Lucas, Matthew C.

Howes, Peter D.

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Article abstract of DOI:10.1016/S0040-4020(98)01096-5

Thioamides may be transformed into thioesters through the simple expedient of warming them in an aqueous THF solution containing an alkylating agent. Reactions proceed in high yield and are amenable to multi-gram scale.

Full text of DOI:10.1016/S0040-4020(98)01096-5

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