Synthesis and dopamine receptor affinities of 1-aminoethylhetero-tetralines

DOI: 10.1016/0223-5234(91)90129-B

Source and publish data:

European Journal of Medicinal Chemistry p. 869 - 874 (1991)

Update date:2022-09-26

Topics:

Authors:

Perrone, R

Berardi, F

Tortorella, V

Govoni, S

Lograno, MD

Daniele, E

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Article abstract of DOI:10.1016/0223-5234(91)90129-B

A series of 1-aminoethylhetero-tetralines 3-6, which can be considered as opened-structure analogues of previously studied dopaminergic compounds 2, were synthesized.In the binding studies, to evaluate D-1 and D-2 activity, no significant affinity was observed towards both dopaminergic receptors.D-1 receptors / D-2 receptors / dopamine / binding / tetralines

Full text of DOI:10.1016/0223-5234(91)90129-B

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