Tetrahedron p. 8067 - 8074 (1990)
Update date:2022-07-29
Topics:
Huang
Kalish
Miller
The carbon framework for carbapenems was constructed by an asymmetric aldol condensation and subsequent direct coupling of the resulting β-hydroxy acid equivalent with an aminophosphonoacetate. Cyclization to the monocyclic β-lactam 20 was followed by oxi
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