Synthesis and N-alkylation of 5-bromomethyl-5-methyl-1,4,7,10-tetraoxa-13-azacyclopentadecane

Article abstract of DOI:10.1055/s-1990-27079

5-Bromomethyl-5-methyl-1,4,7,10-tetraoxa-13-azacyclopentadecane (monoaza-15-crown-5) was prepared by the reaction of 4-bromomethyl-4-methyl-1,8-ditosyloxy-3,6-dioxaoctane, prepared from the corresponding dihydroxy compound, by reaction with bis-(2-hydroxy