Potential Anti-AIDS Drugs. Lipophilic, Adenosine Deaminase-Activated Prodrugs

DOI: 10.1021/jm00109a018

Source and publish data:

Journal of Medicinal Chemistry p. 1647 - 1655 (1991)

Update date:2022-08-04

Topics:

Authors:

Barchi, Joseph J.

Marquez, Victor E.

Driscoll, John S.

Ford, Harry

Mitsuya, Hiroaki

et al. et al.

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Article abstract of DOI:10.1021/jm00109a018

Selected acid-stable (2'-fluoro-2',3'-dideoxyarabinofuranosyl)adenine nucleosides containing methyl groups and other lipophilic functions at various positions in the adenine ring were prepared and evaluated as anti-HIV agents.The N⁶-methyl (1f)

Full text of DOI:10.1021/jm00109a018

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