Direct asymmetric aldol reactions in water with a β-aminosulfonamide organocatalyst

DOI: 10.1016/j.tetasy.2011.05.014

Source and publish data:

Tetrahedron Asymmetry p. 1028 - 1034 (2011)

Update date:2022-08-02

Topics:

Authors:

Miura, Tsuyoshi

Ina, Mariko

Imai, Kie

Nakashima, Kosuke

Yasaku, Yumi

Koyata, Naka

Murakami, Yasuoki

Imai, Nobuyuki

Tada, Norihiro

Itoh, Akichika

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Article abstract of DOI:10.1016/j.tetasy.2011.05.014

Organocatalyst 4 promoted the direct asymmetric aldol reactions of aldehydes with ketones in brine or in the presence of water to afford the corresponding anti-aldol products in moderate to excellent yields with up to 97% ee.

Full text of DOI:10.1016/j.tetasy.2011.05.014

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