Design, synthesis & evaluation of condensed 2H-4-arylaminopyrimidines as novel antifungal agents

DOI: 10.1016/j.ejmech.2014.02.066

Source and publish data:

European Journal of Medicinal Chemistry p. 166 - 175 (2014)

Update date:2022-08-03

Topics:

Authors:

Jain, Kishor S.

Khedkar, Vijay M.

Arya, Nikhilesh

Rane, Prasad V.

Chaskar, Pratip K.

Coutinho, Evans C.

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Article abstract of DOI:10.1016/j.ejmech.2014.02.066

A small, focussed library of condensed 2H-4-arylaminopyrimidines, with 3-diversity points, based on an initial design by molecular docking study of this scaffold at the active site of the fungal enzyme of cytochrome P ₄₅₀ family, lanosterol 14α

Full text of DOI:10.1016/j.ejmech.2014.02.066

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Product name:N-(4-fluorophenyl)-3-(methylthio)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

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