Chiral ligands containing heteroatoms.7. An investigation on the stereochemistry of the ketone reductions by chiral diamines/tin hydride systems

Article abstract of DOI:10.1016/S0957-4166(00)80050-6

Reducing agents prepared from SnCl₂, chiral diamines and diisobutyl aluminum hydride have been applied to the enantioselective reduction of alkyl phenyl and α-alkynyl ketones. The extent of the ee observed was dependent on the hydrolysis temper