Organic Process Research and Development p. 1336 - 1343 (2011)
Update date:2022-08-04
Topics:
Morrison, Henry
Burke, Brenda
Lei, Dennis
Robertson, Vivian
Nagapudi, Karthik
Chan, Johann
Gore, Anu
Fang, Jan
Jona, Jonan
AMG 369 (1), a novel S1P1 agonist, was selected for clinical development for the treatment of multiple sclerosis. Form B of the zwitterionic molecule was initially identified as a potential development form. However, because of the instability
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Doi:10.1016/j.ejmech.2011.05.070
(2011)Doi:10.1039/c8ob01810c
(2018)Doi:10.1021/ja00011a031
(1991)Doi:10.1007/BF00476990
(1990)Doi:10.1002/anie.201103270
(2011)Doi:10.1021/jo201743h
(2011)
