Journal of Medicinal Chemistry p. 1119 - 1131 (1995)
Update date:2022-07-29
Topics: Antipsychotic
Strupczewski
Bordeau
Chiang
Glamkowski
Conway
Corbett
Hartman
Szewczak
Wilmot
Helsley
A series of 3-[[(aryloxy)alkyl]piperidinyl]-1,2-benzisoxazoles was synthesized and evaluated as potential antipsychotic D2/5-HT2 antagonists. Most of these compounds showed potent antipsychotic-like activity in an apomorphine-induced
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