Verapamil analogues with restricted molecular flexibility

DOI: 10.1021/jm00111a043

Source and publish data:

Journal of Medicinal Chemistry p. 2219 - 2225 (1991)

Update date:2022-08-03

Topics:

Authors:

Dei Dei

Romanelli

Scapecchi

Teodori Teodori

Chiarini

Gualtieri

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00111a043

Three analogues with restricted flexibility were designed to study the active conformation of verapamil during interaction with the slow calcium channel. Thus cis- and trans-1-(3,4-dimethoxyphenyl)-4-[N-[2-(3,4-dimethoxyphenyl)ethyl]-N-me thylamino]-r-1-c

Full text of DOI:10.1021/jm00111a043

Products guided by the article

Product name:3-(3,4-dimethoxyphenyl)-1,5-pentanediol

Cas No:133648-77-8

R&D Labs maybe for 133648-77-8

Luzhou North Chemical Co., Ltd.

Contact:+86-830-2796784；+86-830-2796776

Address:Gaoba, Longmatan District, Luzhou, Sichuan Province
Nowa pharmaceuticals Co., LTD

Contact:86-512-69362780,69362785

Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
Afine Chemicals Limited

website:http://www.afinechem.com

Contact:+86-571-85134551

Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China
SPRING CHEMICAL INDUSTRY CO.,LTD

Contact:86-187-66672125

Address:linchi industry park.zouping
Zhongshan Haihong Medicine Co., Ltd.

Contact:86-0760-86925778 （0）18824993998

Address:A7 building,lianyuan road Torch Hi-tech Industrial Development Zone

Relevant to this article

THE 3,4-DIMETHOXYBENZYL MOIETY AS A NEW N-PROTECTING GROUP OF 1,2-THIAZETIDINE 1,1-DIOXIDES.

Doi:10.1016/S0040-4039(00)74875-1
(1991)
A New General Synthesis of 2,2-Dialkyl-2,3-dihydro-4H-pyran-4-ones and Their Application for the in situ Preparation of Electron-Rich Dienes in Carbonyl-Alkyne Exchange Reactions with Acetylenes

Doi:10.1002/hlca.19910740106
(1991)
A direct stereoselective synthesis of (±)-14-deoxyisoamijiol

Doi:10.1016/0040-4039(90)80195-R
(1990)
Cobalt-catalyzed aminocarbonylation of geminal dihaloalkanes. Formation of 2-aminoamide and malonamide derivatives

Doi:10.1016/S0040-4039(00)74885-4
(1991)
Extending the coordination chemistry of cobalt with the metalloligand [Pt₂(μ-S)₂(PPh₃)₄]: Synthesis of the first cobalt(III) derivatives

Doi:10.1016/j.ica.2011.07.006
(2011)
Microsecond charge recombination in a linear triarylamine-Ru(bpy) ₃²⁺-anthraquinone triad

Doi:10.1039/c1cc13831f
(2011)

Article Doi