Enzyme-catalysed hydrolysis of the dibutylester of (±) E,E-2,8-bishydroxymethyl-1,7-dioxaspiro[5,5]undecane

Article abstract of DOI:10.1016/S0957-4166(00)82152-7

The tittle compound was converted into the corresponding (2S,6S,8S) monoester with 94% e.e. by porcine pancreatic lipase (PPL) in water/DMF (9/1).