Bioorganic and Medicinal Chemistry Letters p. 5450 - 5454 (2014)
Update date:2022-08-05
Topics:
Blackburn, Christopher
Barrett, Cynthia
Brunson, Mable
Chin, Janice
England, Dylan
Garcia, Kris
Gigstad, Kenneth
Gould, Alexandra
Gutierrez, Juan
Hoar, Kara
Rowland, R. Scott
Tsu, Christopher
Ringeling, John
Wager, Krista
Xu, He
Acyl derivatives of 4-(aminomethyl)-N-hydroxybenzamide are potent sub-type selective HDAC6 inhibitors. Constrained heterocyclic analogs based on 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine show further enhanced HDAC6 selectivity and inhibitory activity in ce
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