Synthesis and biological properties of some 3-[(N-substituted-amino)pyridinium-4-thiomethyl]-7-[2-(2-amino-thiazol-4-YL)-2 -(Z)-(methoxyimino)acetamido]ceph-3-EM-4-carboxylates

Article abstract of DOI:10.7164/antibiotics.46.1289

The synthesis and antibacterial activity of a series of β-lactamase stable, broad spectrum 7-[2-(2-amino-thiazol-4-yl)-2-(Z)- (methoxyimino)acetamido]-cephalosporins, characterised by a C-3-[N-(substituted-amino)pyridinium-4-thiomethyl] group, is describe