A Facile Synthesis of Bicycloalkan-1-ols. Evidence for Organosamarium Intermediates in the Samarium(II) Iodide Promoted Intramolecular Barbier-Type Reaction

DOI: 10.1021/jo00013a008

Source and publish data:

Journal of Organic Chemistry p. 4112 - 4120 (1991)

Update date:2022-09-26

Topics: Facile Synthesis Samarium(II) iodide

Authors:

Molander, Gary A.

McKie, Jeffrey A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00013a008

Samarium(II) iodide (SmI2) has been successfully employed as a reductive coupling agent for the intramolecular Barbier-type synthesis of bicycloalkan-1-ols.Thus, a variety of 3-(ω-iodoalkyl)cycloalkanones, upon treatment with SmI2 and a catalytic q

Full text of DOI:10.1021/jo00013a008

Products guided by the article

Product name:7,7-Dimethylbicyclo<3.2.1>octan-1-ol

Cas No:134655-22-4

R&D Labs maybe for 134655-22-4

Zhengzhou Minzhong Pharmaceutical Co.,ltd

Contact:0086-371-65797115

Address:15/F,Jiangshan Bldg, NO.126 Huanghe Road,Zhengzhou, China
Nanjing Fred Technology Co.,Ltd.

website:http://www.fredbio.com

Contact:+86-25-84696168

Address:Nanjing
X.T.Y Environ-Tech Co.,Ltd

Contact:+86-310-7092106

Address:Quzhou Modern & New Industrial Park, Handan, Hebei 057250, China
Tianjin Bright Future Technology Co., Ltd

Contact:0086-22-58016666

Address:NO.136 DongTeng Lake Street Tianjin Economic and Technology Development Area,Tainjin,China
Nantong Baokai Chemical Co., Ltd (Hangzhou Baokai Bio-Chemicals Co.,Ltd.)

Contact:+86-513-83886111

Address:No. 68 Suzhou road ,Binjiang Fine Chemical Industrial Park , Beixin town, Qidong city ,Jiangsu province

Relevant to this article

New sulfonyl-containing materials for nonlinear optics: Semiempirical calculations, synthesis, and properties

Doi:10.1021/ja00176a001
(1990)
Synthesis of pro-prodrugs l-lysine based for 5-aminosalicylic acid and 6-mercaptopurine colon specific release

Doi:10.1016/j.ijpharm.2011.09.001
(2011)
Cobalt-mediated [2+2+2] cycloadditions of pyrimidine derivatives to alkynes

Doi:10.1002/(SICI)1521-3765(19991203)5:12<3549::AID-CHEM3549>3.0.CO;2-V
(1999)
Electrochemical carboxylation of cinnamate esters in MeCN

Doi:10.1016/j.tet.2007.10.104
(2008)
Radical Mediated Intramolecular <3-Atom + 2-Atom> Addition and the Synthesis of (+/-)-Rocaglamide: Model Studies

Doi:10.1021/jo00015a008
(1991)
Conformational Study of N-Nitroso-2,6-diphenylpiperidines and N-Nitroso-2,6-diphenylpiperidin-4-ones by Molecular Mechanics Calculations, X-ray Crystallography, and 1H and 13C NMR Spectroscopy

Doi:10.1021/jo00128a011
(1995)

Article Doi