Stereoselective synthesis of trans-4,5-substituted 1,4,5,6-tetrahydropyridine-2-(olates)thiolates

Article abstract of DOI:10.1055/s-1991-26477

trans-4,5-Substituted 1,4,5,6-tetrahydropyridine-2-(olates)thiolates are prepared either from pyridinium salts and cyanoacetic acid derivatives or from pyridinium salts, aromatic aldehydes and ethyl cyanoacetate or cyanoacetamide in the presence of a base