Synthesis of an analogue of D,L-MYO-inositol-1,2-cyclic phosphate: Inhibition of phosphatidylinositol-specific phospholipase C

DOI: 10.1016/S0040-4039(00)79682-1

Source and publish data:

Tetrahedron Letters p. 2207 - 2210 (1991)

Update date:2022-08-05

Topics:

Authors:

Stewart Campbell

Thatcher, Gregory R.J.

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Article abstract of DOI:10.1016/S0040-4039(00)79682-1

A fluorophosphonate analogue of myo-inositol-1,2-cyclic phosphate (cIP) has been synthesized: the specific, potent inhibition of a phosphatidyl inositol-specific phospholipase C (PI-PLC) by this compound is compared with inhibition by vanadate ion.

Full text of DOI:10.1016/S0040-4039(00)79682-1

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